Differential Diagnosis - Peripheral joint involvemnt. 90%. Thoracic Back Pain Red Flags - Physiopedia Differential Diagnosis Practice Questions Flashcards | Quizlet More common in girls/athletes. See table in notes section for differential diagnosis In the paediatric population, must consider infectious causes e.g. If you indicate neck pain/stiffness , The Analyst⢠will ask further questions including this one: Also, normal radiological investigations can miss the scapular assessment unless there is ⦠Differential diagnosis includes cellulitis, septic arthritis, RA, bursitis related to a bunion, sarcoidosis, multiple myeloma, and hyperparathyroidism. Inflammatory arthritis usually causes warm, swollen joints, and extended morning stiffness. Three symptoms (persistent knee pain, limited morning stiffness and reduced function) and three signs (crepitus, restricted movement and bony enlargement) appeared to be the most useful. Polymyalgia rheumatica: Clinical presentation is key to ... However, the evidence available to guide differential diagnosis remains scarce. NR 511 MIDTERM EXAM (VERSION 2) / NR511 MIDTERM EXAM ⦠Stiffness here may be a frozen shoulder or the more difficult to treat post-breast therapy pain syndrome. Osteoarthrosis and arthritis of various origins are most often differentiated - rheumatoid, infectious, metabolic. In this case, therapeutic options would be heavily influenced by the definite diagnosis, given the different approaches to these two main differential diagnoses . Systemic Lupus Erythematosus (SLE) The symptoms of mechanical joint pain can occur in other conditions, which means that making a correct diagnosis can be challenging. Status. Since the diagnosis of KD is essentially clinical, some conditions should be taken into consideration in the differential diagnosis. ⢠Sed rate, Rheum Factor, anti -CCP antibodies, ANA. Metatarsalgia differential diagnosis is usually possible with a careful medical history and physical examination . âHEEL PAINâ: EXPANDING OUR DIFFERENTIAL DIAGNOSIS TO ... Differential of joint pain â¢Age dependent â¢2 year old will not have repetitive use injuries â¢15 year old will not develop growing pains â¢Some gender dependence â¢Adolescent females and knee pain â¢Need to keep a broad differential in mind â¢Think thru the differential â¢The work up â¢And then possible referral Subjective: Symptoms: medial knee pain distal to the joint line. Morning stiffness improves with therapy. ⢠Canât walk up stairs easily. The differential diagnosis of joint pain can be framed with the use of 3 pivotal questions. Unfortunately mold toxicity is not on the radar of many practitioners, and thus they do not include it as part of the differential diagnosis. Certain key historical elements can help narrow the differential diagnosis. Introduction. Paraneoplastic Syndromes. Polymyalgia Rheumatica. It usually responds quickly to once-daily, low-dose prednisone, but some patients require treatment for several years. ⢠No rashes, no fevers, no weight loss, no alopecia. Once this type of arthritis is suspected, possible diagnoses are sorted by ⦠Pain and stiffness in the morning gradually improves with gentle activity and movement during the day. Chronic gouty nephropathy may occur. CT Images of a Severe TMJ Osteoarthritis and Differential Diagnosis with Other Joint Disorders Table 1 Differential diagnosis among osteoarthritis (OA), rheumatoid arthritis (RA), and pain dysfunction syndrome (PDS) [ 3 , 12 , 13 ]. Reactive arthritis. To review the differential diagnosis of monoarthritis with weight loss, click here. The joints most commonly involved are. Inflammation: Definition: Presence of erythema, warmth, swelling, pain with passive ROM, morning stiffness suggests inflammatory cause (arthritis) Stiffness in patients with RA is determined by limitation of motion, which may vary with the time of day. Bone cancer. It may present as constant type pains in the neck or spine or in peripheral joints. The role of a problem representation is therefore to work as an intermediary between a clinical history and a differential diagnosis. Morning stiffness and a history of swelling suggest an inflammatory ⦠Although morning stiffness is a classic feature of more inflammatory joint disease (eg, rheumatoid arthritis [RA]), it is less well recognized as a feature of OA. CPPD arthropathy. ⢠Saw PCP (after a year), ESR 11 25, CRP 11.7 mg/L, RF positive (x2), ANA neg, TSH normal, vit D low (17 ng/mL). While osteoarthritis is a common cause of localized pains, it is over-diagnosed as a cause of widespread aches and pains. In addition to the variable cutaneous manifestations, lesions may be found in... Low Back Pain. Morning stiffness in osteoarthritis is mild and does not exceed 30 minutes (usually 5-10 minutes). The symptoms are progressive and associated with morning stiffness. - Morning pain and stiffness. The disease primarily affects young white men and is characterized by early morning stiffness in the lower back that typically improves with activity. In such patients, however, morning stiffness is brief, constitutional symptoms are absent, and the acute phase reactants are not elevated. Multiple myeloma can present with bone pain and an elevated ESR, thereby ⦠Morning stiffness lasting >60 minutes, improvement of symptoms with physical activity, and awakening at night due to lower back pain may suggest these inflammatory arthritides. Before making such a diagnosis it is necessary to exclude other conditions by establishing that any morning stiffness lasts no more than a few minutes, and that the ESR and SAP levels are normal. Differential Diagnosis of Knee Pain by Anatomic Site. The highly inflammatory nature of RA can make the shoulder sensitive to any type of compression. There are often nail changes present such as yellowing and pitting. The information on the differential diagnosis of osteoarthritis is based on the National Institute of Health and Care Excellence (NICE) clinical guideline Osteoarthritis: care and management [] and expert opinion in review articles on osteoarthritis [Glyn-Jones, 2015], on hip osteoarthritis [Aresti, 2016], and on thumb osteoarthritis and thumb pain [Anakwe, 2011; Dickson, 2015]. There are often nail changes present such as yellowing and pitting. b. than 1 hour; joint swelling and pain, especially at the small joints of the hands, wrists, and feet; symmetrical inflammatory polyarthritis. Engineering, University of Denver. M. A. Paget's disease. These include scarlet fever, staphylococcal toxic shock syndrome, poly-morph erythema, viral infections, systemic-onset juvenile idiopathic arthritis, and polyarteritis no-dosa.The main differential clinical features of these conditions can be ⦠The morning stiffness of RA may persist for hours after the patient awakens, but in OA, morning stiffness usually lasts no longer than 20 to 30 minutes. Probability. If a patient presents Morning Stiffness Differential Diagnosis of Spinal Disease. To review the differential diagnosis of monoarthritis with claudication, click here. Results Recommendations covered the definition of knee OA and its risk factors, subsets, typical symptoms and signs, the use of imaging and laboratory tests and differential diagnosis. Inflammation: Definition: Presence of erythema, warmth, swelling, pain with passive ROM, morning stiffness suggests inflammatory cause (arthritis) Differential diagnosis with arthropathies listed below. The absence of other conditions or symptoms suggesting an alternative diagnosis, such as psoriasis, inflammatory bowel disease (IBD), or a ⦠Your 72-year-old patient has complaints of morning stiffness greater. Morning stiffness and limited mobility of the lumbar spine b. Myelodysplastic Syndrome (MDS) Osteoarthritis. differential diagnosis. To review the differential diagnosis of monoarthritis with morning stiffness, click here. Waking in the morning stiff and in pain, the patient gradually became more supple during the day, feeling at his best from the afternoon until bedtime. Polyarticular arthritis is commonly encountered in clinical settings and has multiple etiologies. Pain and stiffness accelerate during the day and are worse in the evening. The presence of night pain and morning stiffness was significantly associated with sacroiliac-jointsâ bone marrow edema (BME, p < 0.05). Once inflammatory arthritis is suspected, possible diagnoses are sorted by the pattern of joint involvement, which includes number and type of joints involved, symmetry, and onset. The differential diagnosis for polyarthritis is much wider (See Table IV) and includes RA (Figure 2), other connective tissue diseases like lupus, nodal OA (Figure 3), tophaceous gout (Figure 4) and psoriatic arthritis. Nearly two-thirds of the US population will experience neck pain at some point in their lives, and at any one time about 5% of the US population has sufficient neck pain to cause disability. To review the differential diagnosis of back pain, fever and stiffness, click here. Inflammatory Arthritis. If giant cell arteritis is documented by tempo-ral artery biopsy, they suggested that only one Stiffness also varies in characteristics: morning stiffness is the main feature of rheumatoid arthritis, while nighttime stiffness after a day of activity is more of a feature of osteoarthritis. It is asymmetric and can affect small and large joints. Morning stiffness: generally lasting for 1-2 hrs, improves with stretching ⢠Back pain is better with activity, worse with rest ⢠He is able to run cross-country w/out exacerbating his back pain ⢠Has noticed the pain wake him up in the middle of the night 10 The typical symptoms are bilateral aching of the shoulder girdle, associated with morning stiffness. Three symptoms (persistent knee pain, limited morning stiffness and reduced function) and three signs (crepitus, restricted movement and bony enlargement) appeared to ⦠Stiffness is also characteristically different: morning stiffness is the main feature of rheumatoid arthritis versus evening stiffness following a day of activity, which is more characteristic of osteoarthritis. However, inflammatory joint conditions are ⦠Step 3: Rule Out or Confirm each Possible Cause. In contrast, inflammatory arthritis generally causes warm, swollen joints, prolonged morning stiffness, and positive findings on a review of systems. with morning stiffness ⢠Facial rash and body rashes ⢠Alopecia, oral ulcers ⢠No smoking ⢠Fam hx: No autoimmune disease Jaccoudâs arthropathy Case #1: Workup and diagnosis ⢠+ANA 1:320 speckled ⢠+Sm, +SSA ⢠+ribosomal P, +chromatin ⢠+dsDNA 48 ⢠+RF 27, âCCP ⢠Cq1 7 (L) early complement Increases with age. The most useful clinical features supporting a diagnosis of PMR have been included in core inclusion criteria recommended in the BSR/BHPR guideline and are as follows: Age over 50 years. The diagnosis of polymyalgia rheumatica is made primarily on clinical grounds. Presents with other systemic symptoms including symmetric arthritis of the small joints of the hands and feet with morning stiffness are common manifestations. In addition, in most cases the erythrocyte sedimentation rate (ESR) and C ⦠Polymyalgia rheumatica frequently overlaps with giant Confirm. with morning stiffness ⢠Facial rash and body rashes ⢠Alopecia, oral ulcers ⢠No smoking ⢠Fam hx: No autoimmune disease Jaccoudâs arthropathy Case #1: Workup and diagnosis ⢠+ANA 1:320 speckled ⢠+Sm, +SSA ⢠+ribosomal P, +chromatin ⢠+dsDNA 48 ⢠+RF 27, âCCP ⢠Cq1 7 (L) early complement To review the differential diagnosis of back pain and headache, click here. Inflammatory backache, where back pain and stiffness is worse in the early hours of the morning and improves with The neck and hip girdle may also be involved. ⢠Tender, warm, swollen joints ⢠Morning stiffness that lasts for hours ⢠Firm bumps of tissue on arms (rheumatoid nodules) ⢠Fatigue, fever, weight loss ⢠Hands- RA ⦠Rheumatoid arthritis (RA) is the most common inflammatory arthritis, with a lifetime prevalence of up to 1 percent worldwide. a. History, Physical Examination, and Differential Diagnosis of Neck Pain Neck pain is a common and costly problem in Western society. Morning stiffness should be present for <30 minutes. Diagnosis of Knee OA Classic Clinical Criteria established by ACR, 1981 sensitivity 95%, specificity 69% knee pain plus at least 3 of 6 characteristics: > 50 yo Morning stiffness < 30 min Crepitus Bony tenderness Bony enlargement No palpable warmth 5. Fibromyalgia. â Refer to rheumatologist for workup â Learn tests to order to work up for yourself. To review the differential diagnosis of monoarthritis with local erythema, click here. It helps to classify the pain as noninflammatory or inflammatory in origin. â¢Early morning stiffness â¢Symptoms/diagnosis of Crohnâs or UC Orthopaedic Osteoarthritis â¢Elderly â¢Worse on movement (rest helps) and at end of day Septic arthritis â¢Isolated hot, red, swollen joint â¢Agonizingly painful â¢Systemically unwell with fever Other differentials Single joint Sarcoidosis. Raymond H. Kim, M.D. Arthritis: Inflammaed joint. The patient reports vague, poorly localized knee pain, as well as morning stiffness or recurrent effusion. In contrast, inflammatory arthritis generally causes warm, swollen joints, prolonged morning stiffness, and positive findings on a review of systems. Once inflammatory arthritis is suspected, possible diagnoses are sorted by the pattern of joint involvement, which includes number and type of joints involved, symmetry, and onset. Morning stiffness in the joints can last as long as several hours and usually lasts longer than 1 hour. Inflammatory Arthritis. Radiographic findings include bone erosion (eg, periarticular osteopenia or marginal erosions of bone) rather than formation. Although a rare disorder, ankylosing spondylitis is often considered in the differential diagnosis of low back pain. Iâm 34 years old, negative for the gene, with no CRP or ESR abnormalities on labs but have the classic back/SI symptoms that match the profile (early morning pain and stiffness and improvement with movement). considered in the differential diagnosis in patients over 50 years old who present with bilateral achiness and stiffness in the shoulders or hips or both. Bilateral shoulder and/or pelvic girdle aching. Symmetrical inflammation of various joints of the hands and feet (metacarpophalangeal, proximal interphalangeal, wrist, and metatarsophalangeal joints) are the most common initial manifestations of rheumatoid arthritis (RA). Morning stiffness is a cardinal sign of inflammatory arthritis that can appear even before pain and may be related to the accumulation of edema fluid within inflamed tissues during sleep. 6 How is morning stiffness significant in RA? Refining differential diagnosis through testing. Differential Diagnosis Fat pad Pain is located underneath the calcaneus, around the fat pad instead of the ... pain, early morning stiffness in other areas, joint pain and swelling, iritis, digestive or skin problems may further raise suspicion. See Rheumatoid Arthritis diagnosis, screening and evaluations | MIMS Malaysia As the condition becomes chronic, the patient may report morning stiffness and joint deformity, progressive loss of function, or disability. X-ray findings in osteoarthritis are unique because of common cartilage loss and osteophyte formation leading to narrowing of the joint space. Although many people are stiff upon awakening, those with inflammatory arthritis can experience stiffness for an hour or more. Differential Diagnosis and Management of Ankylosing Spondylitis Masked as Adhesive Capsulitis: A Resident's Case Problem ... areas of localized tenderness, and (5) morning stiffness (duration and intensity), using a 10-cm analog scale. To review the differential diagnosis of back pain, fever and stiffness, click here. There must be involvement of a particular skin condition for it to be diagnosed., History of pain, swelling, and morning stiffness for at least 30-60 minutes. Differential of joint pain â¢Age dependent â¢2 year old will not have repetitive use injuries â¢15 year old will not develop growing pains â¢Some gender dependence â¢Adolescent females and knee pain â¢Need to keep a broad differential in mind â¢Think thru the differential â¢The work up â¢And then possible referral As the clinician, you explain to Sam that low back pain is a diagnosis of exclusion. Chronic Fatigue-Fibromyalgia. Sensitivity for diagnosis of SpA was high for IBP (96%) and low for the MRI parameters (26.9â57.4%), and specificity was low for IBP (32%) and high for the MRI parameters (88.3â94.3%). Duration more than 2 weeks. DISH is a chronic age related condition, with characteristic new bone growth at the entheses. Morning stiffness and symmetric swelling of the wrists, PIPs and MCPs constitue the typical history for rheumatoid arthritis. It usually involves the proximal interphalangeal (PIP), metacarpophalangeal (MCP) and wrist joints. , , , , , , Differential diagnosis of osteoarthritis. 6 Scapular malignancies are often missed because they are deep seated and do not manifest till late. The clinical picture in this case is highly suggestive of an inflammatory arthropathy with findings of joint swelling, morning stiffness, and evidence of synovitis. To review the differential diagnosis of back pain and heart murmur, click here. The differential diagnosis formed from the history can then be narrowed down by physical examination and investigations. Denver, Colorado. a. mobility and spine stiffness, may help guide detection in the absence of spinal pain. Polymyalgia rheumatica (PMR) is a common disorder in the elderly population. Certain key historical elements can help narrow the differential diagnosis. (See 'Imaging findings' above.) RESULTS: Recommendations covered the definition of knee OA and its risk factors, subsets, typical symptoms and signs, the use of imaging and laboratory tests and differential diagnosis. The differential diagnosis of pain and dysfunction a challenging task due to the complicated anatomy of the Sacroiliac joint, the Lumbar spine and the buttock area. Bird et al also linked giant cell arteritis with the diagnosis of polymyalgia rheumatica. It is associated with disability, health care expenses, and a loss of wages and productivity. Department of Orthopaedic Surgery I am in the middle of some differential diagnosis detective work. While rare, bone cancer in any area of the body can be lethal if not treated. There must be involvement of a particular skin condition for it to be diagnosed., History of pain, swelling, and morning stiffness for at least 30-60 minutes. Pain and stiffness in upper thighs and hips, never pain below thighs. Patients sometimes report joint swelling and functional difficulties, such as a knee giving way or locking. Differential Diagnosis of Knee Pain November 11, 2016. Assuming a 12.5% background prevalence of knee OA in adults aged â¥45 years, the estimated probability of There is no single diagnostic test, but sets of diagnostic or classification criteria have been suggested by several groups of investigators, ⦠deep aching, boring pain, not relieved by rest-males>Females ->50 yo ... -morning stiffness-M>F-pain eases with physical activity and exercise-positive response to NSAIDs-(-)RF. Other conditions with similar symptoms include inflammatory arthritis (including gout and rheumatoid arthritis), fibromyalgia, neuropathic pain and malignancy [4] .. AM stiffness lasts 4 hours. Adjunct Associate Professor of Bioengineering, Department of Mechanical and Materials . Some of the common symptoms of toxic mold and CIRS are: 1. Inflammatory arthritis: can involve small joints, large joints, or the spine; tends to be symmetric, though some forms are asymmetric; patients may present with morning stiffness or âgellingâ with inactivity lasting >1 hr; joint use typically improves symptoms unless other conditions (eg, osteoarthritis, trauma) exist; constitutional symptoms and extra-articular ⦠For people below the age of 40, the diagnosis of OA can be made with exactly the same approach, however the likelihood of OA is relatively reduced. Morning stiffness is a classic finding. In this case, an appropriate diagnosis led to improvement in the management strategy of what might have appeared to be unrelated shoulder pain. A differential diagnosis of your symptoms and risk factors finds the likely cause of severe morning stiffness: Cause. Approach to Joint Pain: 3. Choice E: Rheumatoid arthritis is also an inflammatory arthritis associated with swelling and redness, morning stiffness lasting longer than 30 minutes, and joint pain that gets better with activity. Sjogren Syndrome. Evidence of an acute phase response. Low Testosterone. Hart and colleagues were the first to accurately describe symptoms of inflammatory back pain in 1949: âA frequent feature of the pain and stiffness was the aggravation caused by. Osteoarthritis. Persistent axial pain that slowly tapers after the initiation of increasing... Idiopathic connective tissue disorders. Inflammatory backache, where back pain and stiffness is worse in the early hours of the morning and improves with There may also be constitutional symptoms. Rheumatoid arthritis is associated with prominent, prolonged (>1 hour) morning stiffness and overtly swollen, warm joints. List at least three differential diagnoses you will explore for this patient. DISH represents the best example of enthesogenic osteoarthritis- a type of osteoarthritis that is exclusively related to the enthesis. The evaluation of a patient with joint pain calls for a detailed history and physical exam (often focusing on extra-articular findings) and occasionally the sampling of joint fluid and possibly analyzing radiologic and serologic tests. The differential diagnosis of joint pain can be framed with the use of 3 pivotal questions. The diagnosis is even challenged more by the inconsistency of MRI findings and imaging with the symptoms leading to misdiagnosing the conditions. d. Pain is brought on by activity and resolves predictably with rest. The morning stiffness feeling often lasts more than an hour. Other inflammatory arthritides could also be considered. Hand To review the differential diagnosis of back pain and headache, click here. Results Recommendations covered the definition of knee OA and its risk factors, subsets, typical symptoms and signs, the use of imaging and laboratory tests and differential diagnosis. STUDY. The diagnosis is based upon recognition of a clinical syndrome, consisting of pain and stiffness in the shoulder and pelvic girdle, muscle tenderness of the upper and lower limbs and nonspecific somatic complaints. Thinking about the differential diagnosis. To review the differential diagnosis of back pain and heart murmur, click here. Lyme Disease. Three symptoms (persistent knee pain, limited morning stiffness and reduced function) and three signs (crepitus, restricted movement and bony enlargement) appeared to be the most useful. 2. Hip OA is the second most common large joint OA. Radiograms of hands and wrists M. Parodi . A condition involving any of the bursae lying between the various tendons of the superficial pes anserinus, of a bursa between the MCL and superficial pes anserinus. Patients with a spondyloarthropathy may have a history of bilateral sacroiliac joint pain associated with morning stiffness that may be present for years without a specific diagnosis. It is asymmetric and can affect small and large joints. âNoninflammatory arthritis, which is mostly related to osteoarthritis, does not have inflammatory features, such as warm or swollen joints. [ 3 ] [ 55 ] If stiffness persists for longer than this, other diagnoses should be considered, such as rheumatoid arthritis (RA). The history of the presenting complaint is a key component of establishing a diagnosis and should be divided into three subsections to ensure that the most crucial points in the history are dealt with at an early stage. Severe muscle tenderness should suggest another differential diagnosis, including fibromyalgia or a regional pain disorder. The Analyst⢠is our online diagnosis tool that learns all about you through a straightforward process of multi-level questioning, providing diagnosis at the end. ⢠Morning stiffness lasting longer than 1 hour ⢠Age over 65 years ⢠Depression and weight loss ⢠Bilateral tenderness in arm muscles. Anterior knee pain. An elevated SU (>8.0mg/dL) may support the diagnosis of a gout flare but is not itself diagnostic. erosive) Rheumatoid arthritis. 24 Patients with reactive arthritis and psoriatic spondylitis may develop unilateral sacroiliac disease associated with low back pain that is lateralized to the affected side. Palindromic rheumatism. The differential diagnosis for polyarthritis is much wider (See Table IV) and includes RA (Figure 2), other connective tissue diseases like lupus, nodal OA (Figure 3), tophaceous gout (Figure 4) and psoriatic arthritis. To review the differential diagnosis of back pain and horner's syndrome, click here. Extra-articular manifestations ⦠Rarely, malignancies around the humerus or scapula can create shoulder stiffness. One of the most important and helpful criteria in reaching a diagnosis is the blood test to identify a specific set of antibodies that are known biomarkers for assessing rheumatoid arthritis. Limited morning stiffness; Reduced function; One or more of crepitus (noise on movement); restricted movement; bony enlargement. immobility. Inflammatory arthritis always secondary to another condition. The first step is to distinguish between true articular pain and nonarticular or periarticular conditions by recognizing clinical patterns through the history and physical examination. Prolonged morning stiffness is a good clue to an inflammatory arthritis. Colorado Joint Replacement. Like many autoimmune diseases, the etiology of RA is multifactorial. Definition. The differential diagnosis of this patientâs arthritis in- cluded a relapse of polymyalgia rheumatica, with periph- eral involvement or elderly onset rheumatoid arthritis (EORA) that had had a polymyalgia-like pattern of onset more than 2 years before. Differential diagnosis, Diagnosis, Premenstrual syndrome, CKS ... Fibromyalgia â presents with pain associated with generalized morning stiffness that is worsened by stress, cold, and activity. Summary. PLAY. Patients with reactive arthritis and ⦠We perform a thorough medical history, with particular attention to joint pain, reported swelling, and the presence, location (peripheral joints rather than low back), and duration (at least 30 minutes) of morning stiffness. 5. Reading the above problem representation, rheumatoid arthritis comes to mind. Back pain is a common presentation to the Emergency Department. Tiny Tip: Back Pain Differential Mnemonic. Morning stiffness lasting more than 45 minutes. Early differential diagnosis is important, as emerging interventions show promise when used earlier in Morning stiffness is another typical symptom of living with ankylosing spondylitis. Gout. Common in novice swimmers and long-distance runners (Dutton).
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